Can't debug on Android 6.0 Marshmellow

So I used to have this working on 5, after an update to Android 6 I’m unable to get USB debugging to work. Anyone else run into this?

  • I’ve enabled USB debugging on the device.
  • I’ve tried three different USB cables
  • there are no options under storage & USB for, well, USB
  • I tried downloading the LG G4 unified drivers for OSX